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Earstim is a wearable electro-stimulator which has the ability to reduce the symptoms of Parkinson’s disease such as tremor, slow movement and limb rigidity to the level achieved with medication in a noninvasive manner. The development of the device was initiated with the research carried out at Koc University by its inventor, Assoc. Prof. Yusuf Özgür Çakmak, and progressed to this day thanks to the support provided by Inventram and the determination of the project team.

Currently, patients suffering from Parkinson’s use a number of medications for the treatment of their symptoms. However, these medications have many psychological and physiological side effects, examples of which are involuntary movement or personality disorders. Patients in the advanced stages of the disease may resort to a surgical procedure called the Deep Brain Stimulation. This procedure involves the implant of an electrode in a specific part of the brain and requires a pulse generator, or battery pack, to be implanted in the chest or collarbone area. For this reason, it is a considerably risky and expensive method of treatment.

The device will not only replace the dependency on medication but it will also offer an alternative to the Deep Brain Stimulation procedure. As the device is wearable and easy to use, it increases the comfort of the patient. The main objective of this device is to carry Parkinson’s disease patients’ quality of life to the utmost level.


Parkinson's Disease

Parkinson’s disease is a result of neuronal loss, specifically the dopaminergic neurons located in the midbrain. However, the reason for such neuronal loss is yet to be discovered.

The disease is the second most common neurodegenerative disease in the world after Alzheimer’s. The disease typically occurs in people who are 50; however, it can also be observed at a younger age.

Common symptoms of the disease are tremors, rigidity, slow movement, poor balance; and as the disease progresses, so do the symptoms. In the advanced stages of the disease, patients may experience difficulty walking and talking, and may eventually find it impossible to meet their basic daily needs without assistance.

There is no treatment for this progressive disease; however, with a variety of medications or a surgical procedure which involves implanting a device in the brain, it is possible to alleviate the symptoms of the disease.


Assoc. Prof. Yusuf Ozgur Cakmak

Inventor & Chief Scientific Officer

Prof. Hakan Ürey

Inventor & Technology Advisor

Yalın Geçer

Business Development Director

Burak Ozsoy, PhD

Operations Manager


All intellectual property rights relating to the device belong to Inventram and they will be transferred to the company that will be established. 

There are two patent portfolios regarding the invention. The first patent was granted in USA, Europe (13 countries), Japan, China and Russia. It is also pending in Canada, Korea, and Israel.

The second patent portfolio completed PCT with positive report and now local entrance is in progress.